Heavy chain gene rearrangement

Heavy chain gene rearrangement is a process that occurs in immune cells called B cells, enabling them to produce a diverse array of antibodies. During this process, specific gene segments within the DNA are cut and rejoined in different combinations, creating unique antibody genes tailored to recognize many different germs. This gene shuffling occurs in the bone marrow and allows the immune system to generate a vast variety of antibodies, each capable of binding to a different pathogen. Essentially, heavy chain gene rearrangement is the biological method that helps us develop a flexible and effective immune defense.