HBOC mutation

HBOC mutations refer to changes in specific genes, primarily BRCA1 and BRCA2, that significantly increase the risk of developing certain cancers, especially breast and ovarian cancer. These genetic alterations affect how cells repair DNA damage, leading to a higher chance of abnormal growth. People with HBOC mutations can pass these changes to their children. Identifying these mutations helps guide personal risk management, including increased screening or preventive options. It's important to note that not everyone with the mutation will develop cancer, but it indicates a higher predisposition compared to the general population.