Guidelines for the management of TRALI

TRALI (Transfusion-Related Acute Lung Injury) is a rare but serious reaction to a blood transfusion, causing sudden lung inflammation and difficulty breathing. Management involves stopping the transfusion immediately, providing oxygen therapy, and supporting breathing—sometimes with mechanical ventilation if needed. Patients are closely monitored in a hospital setting. Treatment focuses on maintaining oxygen levels and supporting the lungs until the inflammation decreases. It's also important to identify and treat any underlying causes. Early recognition and prompt care are critical for a good outcome.