Guanylate cyclase activating proteins

Guanylate cyclase activating proteins (GCAPs) are molecules that help regulate vision by controlling an enzyme called guanylate cyclase in the eye’s retina. When light hits the eye, GCAPs sense the change in calcium levels and either activate or inhibit guanylate cyclase accordingly. This regulation helps maintain the proper levels of a signaling molecule called cyclic GMP, which is essential for converting light into neural signals. In summary, GCAPs act as messengers that fine-tune visual responses, ensuring clear and accurate vision under varying light conditions.