Granulomatosis with Polyangiitis (GPA)

Granulomatosis with Polyangiitis (GPA) is a rare autoimmune disease that causes inflammation of blood vessels, affecting various organs, primarily the lungs, kidneys, and sinuses. This condition leads to the formation of small clusters of immune cells called granulomas, which can damage tissues and disrupt normal function. Symptoms often include sinusitis, cough, kidney issues, and fatigue. The exact cause is unknown, but it may involve a combination of genetic and environmental factors. Treatment typically includes medications to reduce inflammation and suppress the immune system, helping to manage symptoms and prevent complications.