Granulomatosis with Polyangiitis

Granulomatosis with Polyangiitis (GPA) is a rare autoimmune disorder where the immune system mistakenly attacks blood vessels, causing inflammation and damage primarily in the lungs, kidneys, and respiratory tract. This inflammation can lead to symptoms like persistent sinus issues, nosebleeds, coughing, and kidney problems. The exact cause isn’t known, but it involves abnormal immune responses leading to granulomas—clusters of immune cells—and blood vessel inflammation. Although serious, GPA is treatable with medications that suppress the immune system, helping to control inflammation and prevent organ damage. Early diagnosis and ongoing management are essential for better outcomes.