
Gli protein
Gli proteins are a family of transcription factors that play a key role in the Hedgehog signaling pathway, which is crucial for cell development and growth. When the pathway is activated, Gli proteins move into the cell nucleus and regulate the expression of genes involved in tissue patterning and cell differentiation. They function like molecular switches, turning genes on or off in response to signals, helping cells grow and develop properly. Proper regulation of Gli proteins is essential for normal development, and their malfunction can contribute to diseases such as cancer.