GH receptor signaling pathway

The growth hormone (GH) receptor signaling pathway begins when growth hormone binds to its specific receptor on a cell’s surface. This activates the receptor, which then triggers internal signals through molecules like JAK2 and STATs. These signal molecules travel to the cell nucleus, prompting the production of proteins that promote growth, cell division, and metabolism. This pathway helps regulate growth, tissue repair, and energy use. Essentially, GH binding starts a chain of events inside the cell that lead to growth-related effects throughout the body.