Germline gene therapy

Germline gene therapy involves modifying the genes in reproductive cells (sperm or eggs) to correct or alter genetic conditions. Because these changes are in cells that contribute to future generations, the modifications can be inherited by offspring. This approach aims to prevent genetic disorders before birth, potentially eliminating inherited diseases from a family line. However, it raises ethical and safety concerns due to its heritable impact, and it is currently regulated or restricted in many countries. Overall, germline gene therapy offers the possibility of permanently reducing genetic health issues, but careful consideration of its implications is essential.