Genome-scale Metabolic Models

Genome-scale metabolic models are comprehensive computer representations of an organism's metabolism, capturing all known biochemical reactions based on its genetic information. They help scientists understand how a cell processes nutrients, produces energy, and synthesizes essential compounds. By simulating these metabolic networks, researchers can predict how an organism responds to changes, such as gene mutations or drug treatments. These models are valuable tools in fields like medicine, biotechnology, and environmental science, enabling the optimization of microbial production, understanding disease mechanisms, and designing new therapies by accurately reflecting the organism's metabolic capabilities.