Genome integrity

Genome integrity refers to the preservation of the complete and accurate sequence of an organism's DNA, which contains all genetic information necessary for growth, development, and functioning. Maintaining genome integrity involves protecting DNA from damage caused by environmental factors, replication errors, or cellular stress, and repairing any harm that occurs. When genome integrity is compromised, it can lead to mutations or genetic instability, which may contribute to diseases like cancer. Healthy cells have mechanisms to detect, repair, and prevent DNA damage, ensuring the stability of genetic information across generations.