Genome Aggregation Database

The Genome Aggregation Database (gnomAD) is a large collection of genetic data from over 140,000 individuals worldwide. It consolidates DNA information to provide insights into the frequency of genes and genetic variants in different populations. Researchers and healthcare professionals use gnomAD to better understand normal genetic variation, identify rare or disease-causing mutations, and improve diagnostics. By offering a comprehensive reference of human genetic diversity, gnomAD helps advance medical research, personalized medicine, and our knowledge of human biology, while carefully excluding data from individuals with known genetic disorders to ensure accurate population-level analyses.