genetics of Alzheimer's disease

Alzheimer’s disease has a genetic component, meaning certain genetic factors can influence the risk of developing it. Some genes, like APOE ε4, increase the likelihood, but not everyone with these genes will develop the disease. Most cases are influenced by a combination of genetics, age, and lifestyle. Rare forms of familial Alzheimer's are caused by specific gene mutations that almost guarantee the disease will develop, usually at a younger age. Overall, genetics help us understand susceptibility, but they are just one part of a complex interplay with environmental and health factors in Alzheimer's development.