"Gadolinium-based contrast agents and nephrogenic systemic fibrosis"

Gadolinium-based contrast agents are medications used in MRI scans to improve image clarity. Gadolinium, a metal, is attached to a carrier molecule and injected into the bloodstream. While generally safe, in people with kidney problems, the body's inability to efficiently clear gadolinium can lead to a rare but serious condition called nephrogenic systemic fibrosis (NSF). NSF causes thickening and hardening of the skin and other tissues, potentially leading to mobility issues. Therefore, healthcare providers assess kidney function before administering gadolinium contrast to minimize this risk.