GABAergic signaling

GABAergic signaling involves the neurotransmitter GABA (gamma-aminobutyric acid), which mainly acts as the brain's primary calming agent. When GABA is released by nerve cells, it binds to specific receptors on neighboring neurons, reducing their activity. This inhibitory effect helps regulate brain excitability, preventing excessive nerve firing that can lead to issues like anxiety, seizures, or over-stimulation. GABAergic signaling is vital for maintaining a healthy balance between brain excitation and inhibition, supporting relaxation, sleep, and overall neurological stability.