Fragment-based drug discovery

Fragment-based drug discovery (FBDD) is a method used to develop new medicines by identifying small chemical pieces, called fragments, that can bind to specific parts of a target protein involved in disease. These fragments are simpler and smaller than typical drugs, making them easier to analyze and optimize. Once a fragment binds to the target, scientists modify and combine these fragments to create more effective, larger molecules that can precisely interfere with the protein's activity. This approach often leads to the discovery of new drugs more efficiently than traditional methods.