FOXO (Forkhead box O)

FOXO (Forkhead box O) refers to a group of proteins that act as transcription factors, meaning they help control which genes are turned on or off in cells. They play a vital role in processes like cell growth, survival, metabolism, and stress response. FOXO proteins are sensitive to signals such as insulin and oxidative stress, and they help maintain cellular health by promoting repair mechanisms and preventing damage. Their activity is tightly regulated by various pathways, making them crucial for aging, cancer prevention, and metabolic balance.