Image for FOXN1 (Forkhead box N1)

FOXN1 (Forkhead box N1)

FOXN1 (Forkhead box N1) is a gene that encodes a protein functioning as a transcription factor, which helps regulate the expression of other genes. It plays a critical role in the development and maturation of the thymus gland, an organ important for the immune system. Proper FOXN1 activity is essential for the production of T-cells, a type of immune cell that defends the body against infections. Mutations in this gene can lead to immune deficiencies, such as the "nude" phenotype, characterized by a lack of hair and compromised immunity. In summary, FOXN1 is vital for immune system development and overall health.