forward mutation assay

A forward mutation assay is a scientific test used to detect changes, or mutations, in the DNA of living cells. It involves exposing cells to a substance to see if it causes mutations that restore or produce a specific trait, like the ability to grow in a special growth medium. If the cells develop this trait after exposure, it indicates that mutations have occurred in their DNA due to the substance. This test helps assess the potential of chemicals or environmental factors to cause genetic mutations, which can be related to cancer or genetic disorders.