formalin-fixed paraffin-embedded (FFPE)

Formalin-fixed paraffin-embedded (FFPE) is a method used in medical and research labs to preserve tissue samples. In this process, tissue is first treated with formalin to prevent decay and preserve cellular structures. Then, it is embedded in paraffin wax, which allows thin slicing for examination under a microscope. FFPE samples are stable for long periods, enabling detailed study of tissue architecture and cellular details, which is essential for diagnosis, research, and testing. This technique maintains the tissue’s morphology and protein integrity, making it a standard method in pathology labs worldwide.