FMF gene

The FMF gene, also known as MEFV, provides instructions for making a protein called pyrin, which helps regulate inflammation in the body. Proper function of this gene is important for controlling how the immune system responds to infections or other triggers. Mutations or changes in the FMF gene can lead to increased inflammation, causing a condition known as Familial Mediterranean Fever (FMF). This disorder results in episodes of fever and pain, often in the abdomen, chest, or joints. Understanding the FMF gene helps diagnose and manage this inherited condition, improving patient outcomes by guiding targeted treatment.