Image for Feulgen Reaction

Feulgen Reaction

The Feulgen reaction is a special staining method used in microscopy to identify DNA in cells. It involves treating cells with an acid that breaks down DNA's sugar component, creating sites where a dye called Schiff’s reagent can bind. When this dye binds to the DNA, it produces a distinct magenta color, allowing scientists to see and measure DNA within cells. This technique is useful in research and diagnosis, helping to analyze cell proliferation, genetic material, or detect abnormalities by visualizing DNA presence and quantity.