Familial Focal Segmental Glomerulosclerosis (FSGS)

Familial Focal Segmental Glomerulosclerosis (FSGS) is a hereditary kidney disorder characterized by scarring (sclerosis) in parts of some glomeruli, the tiny filtering units in the kidneys. This scarring impairs the kidneys’ ability to filter blood properly, often leading to protein loss in the urine, swelling, and potential kidney failure. The condition runs in families, indicating a genetic component. It can affect people of various ages and may require treatments like medications or dialysis. Understanding its genetic basis helps in diagnosis and tailoring management strategies for affected individuals.