extracellular signal-regulated kinase (ERK)

Extracellular signal-regulated kinase (ERK) is a protein involved in transmitting signals from the outside to the inside of cells. It is part of a signaling pathway that helps cells respond to various stimuli, such as growth factors or stress, by regulating activities like division, movement, or survival. When activated, ERK moves into the cell nucleus and influences gene expression, which affects how the cell behaves. Proper ERK functioning is essential for normal development and tissue health, but when dysregulated, it can contribute to diseases like cancer.