experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is a research model used to study multiple sclerosis (MS), a disease where the immune system mistakenly attacks the brain and spinal cord. In EAE, scientists induce an immune response in animals, like mice, that targets their nerve coverings called myelin. This causes inflammation and nerve damage similar to MS symptoms such as paralysis, weakness, and sensory issues. Researchers use EAE to understand disease mechanisms and test potential treatments, helping us learn how autoimmune attacks affect neural tissues and find ways to prevent or slow MS progression.