Evidence-based guidelines for TRALI prevention

Evidence-based guidelines for preventing Transfusion-Related Acute Lung Injury (TRALI) involve careful blood donor management and testing. Strategies include screening donors for antibodies that might cause lung reactions, especially those who have been pregnant or recently given birth, since they are more likely to have these antibodies. Blood banks also prefer using plasma from male donors or women who have never been pregnant, reducing risk. Additionally, monitoring recipients closely and limiting the use of transfusions when not absolutely necessary help prevent TRALI. Implementing these measures has been proven effective in decreasing TRALI cases and improving transfusion safety.