Image for Eukaryotic translation initiation factor 4E (eIF4E)

Eukaryotic translation initiation factor 4E (eIF4E)

Eukaryotic translation initiation factor 4E (eIF4E) is a protein that plays a crucial role in starting the process of making proteins in human cells. It specifically helps recognize and bind to the “cap” structure at the beginning of messenger RNA (mRNA), the molecule that carries genetic instructions from DNA to produce proteins. By attaching to this cap, eIF4E helps recruit other factors needed to assemble the machinery that translates mRNA into amino acids, ultimately forming functional proteins. It is essential for proper cell function, growth, and response to signals, and its activity is carefully regulated to maintain cellular health.