ET-3 gene

The ET-3 gene, also known as EDN3, provides instructions for making a protein called endothelin-3. This protein plays a key role in the development and function of the nervous system, blood vessels, and pigmentation in the skin. It helps regulate cell growth and communication within these systems. Mutations or changes in the ET-3 gene can affect these processes, potentially leading to health issues such as pigmentary disorders or certain neuroendocrine conditions. Overall, ET-3 is important for normal development and functioning of various tissues in the body.