ERK1/2

ERK1 and ERK2 are proteins that function as part of a critical cell communication pathway called the MAPK/ERK pathway. This pathway transmits signals from outside the cell to its interior, influencing processes like cell growth, division, and survival. When specific signals, such as growth factors, bind to receptors on the cell surface, ERK1/2 become activated through a series of chemical steps. Once active, they move into the nucleus to help turn on genes that promote cell proliferation and other responses. Proper regulation of ERK1/2 is essential for healthy cell function; abnormal activity can lead to diseases like cancer.