endothelin signaling pathway

The endothelin signaling pathway involves endothelin, a powerful peptide molecule produced mainly by cells lining blood vessels. It binds to specific receptors on nearby cells, causing blood vessels to constrict or narrow. This process helps regulate blood pressure and blood flow. Endothelin also influences cell growth and inflammation. The pathway is important for maintaining vascular health but can contribute to conditions like hypertension when overactive. Understanding this signaling helps in developing treatments for cardiovascular diseases, ensuring blood pressure is kept within healthy limits.