Endothelin receptor antagonists

Endothelin receptor antagonists are medications that block the effects of endothelin, a natural substance in the body that constricts blood vessels and increases blood pressure. By inhibiting these receptors, the drugs help relax and widen blood vessels, improving blood flow and reducing pressure in conditions like pulmonary arterial hypertension. This targeted action helps ease the workload on the heart and improves symptoms, offering an effective treatment option for certain vascular diseases.