EGFR mutation

EGFR mutation refers to a change in the EGFR gene, which provides instructions for making a protein called the epidermal growth factor receptor. This receptor plays a key role in cell growth and division. In some cancers, such as certain lung cancers, mutations in EGFR cause the receptor to become abnormally active, leading to uncontrolled cell growth and tumor development. Identifying these mutations is important because targeted therapies can be used to block the abnormal receptor, helping to control or treat the cancer more effectively.