Drug-drug interactions in transplantation

Drug-drug interactions in transplantation occur when medications used to prevent organ rejection or manage health conditions affect each other's effectiveness or cause side effects. Some drugs may increase or decrease the levels of immunosuppressants, risking organ rejection or toxicity. For example, certain antibiotics or antifungal medications can interfere with immunosuppressants, making them less effective or more toxic. Managing these interactions involves careful medication planning and monitoring to ensure the transplanted organ remains healthy while minimizing side effects. This coordination helps optimize treatment outcomes and patient safety.