DNase-seq

DNase-seq is a laboratory technique used to identify regions of DNA that are accessible and not tightly packed within the cell. It involves treating cells with an enzyme called DNase I, which cuts DNA that is open and active, such as regions where genes are turned on. The cut DNA fragments are then sequenced to map these accessible areas across the genome. This information helps scientists understand gene regulation and how cells control which genes are active, providing insights into cell function and identity.