DNA-PKcs (DNA-dependent protein kinase catalytic subunit)

DNA-PKcs (DNA-dependent protein kinase catalytic subunit) is an essential enzyme involved in repairing DNA damage, particularly in fixing double-strand breaks caused by radiation or other stress. It works as part of a larger complex called DNA-PK, which senses the damage and helps orchestrate the repair process. By recognizing broken DNA strands, DNA-PKcs activates and coordinates other repair proteins to efficiently restore the DNA’s integrity, maintaining genetic stability. Its proper function is vital for preventing mutations that could lead to diseases like cancer.