DNA-encoded libraries

DNA-encoded libraries are collections of many different chemical compounds, each linked to a unique DNA sequence that acts as a molecular barcode. This linkage allows scientists to quickly identify which compounds bind to specific target molecules, such as proteins. By mixing the entire library with the target, binding compounds can be isolated, and their DNA sequences read to determine their structures. This method streamlines drug discovery by enabling rapid screening of vast numbers of compounds simultaneously, saving time and resources compared to traditional approaches.