direct immunofluorescence testing

Direct immunofluorescence testing is a laboratory technique used to detect specific immune substances, like antibodies or proteins, in a tissue sample. A fluorescent dye is attached to a special antibody that binds directly to the target substance in the tissue. When examined under a special microscope that uses UV light, the fluorescent dye glows, indicating the presence and location of the target. This test helps diagnose autoimmune and skin diseases by revealing abnormal immune activity directly in the affected tissues.