Direct Immunofluorescence

Direct immunofluorescence is a laboratory technique used to detect specific proteins or antibodies in a skin or tissue sample. A special fluorescent dye is attached to an antibody that binds directly to the target molecule in the tissue. When examined under a microscope with UV light, the dye emits a bright glow, revealing the presence and location of the proteins or antibodies. This method helps diagnose autoimmune or immune-related skin diseases by providing clear, visual evidence of immune system activity in the tissue sample.