Desmosomes

Desmosomes are specialized connections between neighboring cells, acting like rivets or anchors that hold the cells together tightly. They are primarily found in tissues subject to stretching, such as the skin and heart. Desmosomes use intermediate filaments—strong, thread-like structures within cells—and protein complexes to form these links, providing mechanical strength and stability. By anchoring cells together, desmosomes help tissues resist mechanical forces and maintain their integrity during movement and stress. This connection is vital for the structural cohesion of many tissues, ensuring they function properly under dynamic conditions.