Image for density gradient centrifugation

density gradient centrifugation

Density gradient centrifugation is a laboratory technique used to separate particles or cells based on their density. A tube is filled with a special, layered solution with varying densities. When a mixture of cells or particles is placed on top and the tube is spun rapidly in a centrifuge, each component moves through the layers until reaching the point where its density matches the surrounding solution. This allows different types of cells or particles to be isolated efficiently for research or medical analysis. The method is precise and useful for separating complex biological samples.