
DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin)
DC-SIGN is a specialized receptor found on certain immune cells called dendritic cells. Its primary role is to recognize and bind specific molecules on the surface of pathogens like viruses, bacteria, and fungi. By doing so, DC-SIGN helps the immune system identify and respond to potential threats. It also assists in transporting these microorganisms to lymph nodes, where immune responses are coordinated. Understanding DC-SIGN is important for developing strategies to prevent infections and design vaccines, as it plays a key role in how our immune system detects and interacts with various pathogens at a cellular level.