Cytogenetics in CLL

Cytogenetics in chronic lymphocytic leukemia (CLL) involves studying the chromosomes—structures that carry genetic information—within the cancer cells. By examining these chromosomes, doctors can identify specific abnormalities or changes that influence how the disease progresses and responds to treatment. These genetic markers help in classifying the disease, predicting patient outcomes, and tailoring personalized therapy strategies. Techniques like fluorescence in situ hybridization (FISH) are commonly used to detect these chromosome changes precisely. Overall, cytogenetics provides valuable insights into the biology of CLL, aiding in more effective management of the disease.