CYP21A2 (Cytochrome P450 21A2)

CYP21A2, also known as Cytochrome P450 21A2, is a gene that produces an enzyme crucial for making hormones called cortisol and aldosterone in the adrenal glands. These hormones help regulate stress response, blood pressure, and salt balance in the body. When there are mutations or changes in this gene, it can lead to a condition called congenital adrenal hyperplasia (CAH), affecting hormone production and causing issues like electrolyte imbalances and abnormal development. Understanding CYP21A2 is important for diagnosing and managing these hormonal disorders.