cryopyrin-associated periodic syndromes (CAPS)

Cryopyrin-associated periodic syndromes (CAPS) are a group of rare genetic disorders characterized by episodes of inflammation that can affect multiple parts of the body. These conditions result from a mutation affecting the immune system's regulation, leading to excessive production of inflammatory substances called cytokines. Symptoms may include recurrent fevers, skin rashes, eye redness, joint pain, and fatigue. CAPS can vary in severity, from mild to more severe forms that impact multiple organs. Treatment typically involves medications that block inflammation, helping to control symptoms and prevent complications.