cryopyrin-associated periodic syndromes

Cryopyrin-associated periodic syndromes (CAPS) are a group of rare genetic disorders caused by an overactive immune response, leading to excessive inflammation. This results in recurring symptoms like fever, rash, joint pain, and fatigue. CAPS are due to mutations affecting a protein called cryopyrin, which triggers inflammatory signals. The condition can vary in severity, from mild to severe, and often responds well to treatments that block the inflammatory process. Understanding and managing CAPS is important to reduce symptoms and prevent complications.