cryo-EM workflow

Cryo-electron microscopy (cryo-EM) is a technique used to visualize tiny biological structures at near-atomic resolution. The process involves freezing a sample of molecules rapidly in ice to preserve their natural form. These frozen samples are then exposed to a powerful electron microscope, which captures many images from different angles. Special software processes these images to create detailed 3D reconstructions of the molecules. This method allows scientists to study the structure of complex biological entities, like proteins and viruses, helping to understand their function and develop new medicines.