Cre-Lox recombination

Cre-Lox recombination is a genetic technique used to selectively modify DNA within an organism. It involves two key components: the Cre enzyme and specific DNA sequences called LoxP sites. When the Cre enzyme encounters LoxP sites flanking a gene or DNA segment, it recognizes and cuts at these sites, allowing the removal or inversion of that segment. This method enables precise, controlled genetic alterations in specific tissues or at particular times, making it a valuable tool for studying gene function, creating disease models, and developing advanced biotechnology applications.