COX inhibitors

COX inhibitors are medications that reduce pain, inflammation, and fever by blocking cyclooxygenase (COX) enzymes, which are involved in producing prostaglandins—body chemicals that promote inflammation and pain. There are two main types: COX-1, which protects stomach lining and supports blood clotting; and COX-2, which mainly triggers inflammation. Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin inhibit these enzymes to relieve symptoms. While effective, they can cause side effects such as stomach irritation or increased bleeding risk, especially if used long-term.