Combined Immunodeficiencies

Combined Immunodeficiencies are a group of disorders where both parts of the immune system—the cells that target specific germs (T cells) and those that produce antibodies (B cells)—do not function properly. This makes individuals more susceptible to infections, as their bodies struggle to fight off bacteria, viruses, and other pathogens. These conditions can be caused by genetic mutations, and symptoms often appear in infancy or early childhood. Early diagnosis and treatment, including medications or bone marrow transplants, are essential to help manage the symptoms and improve quality of life.