Cobalt Staining

Cobalt staining is a diagnostic technique used in microscopy to identify specific structures or substances within biological tissues and cells. It involves applying a solution containing cobalt ions, which bind selectively to certain cell components, such as glycogen or specific enzymes. When viewed under a microscope, the cobalt reacts with these targets, producing a distinct coloration that helps identify and study the tissue’s chemical makeup. This method enhances visualization and aids in the diagnosis or research of various medical and biological conditions.